Top 10 Semi-Automatic Cartridge Filler Manufacturers in USA (2025)

In 2025, a number of equipment manufacturers in the U.S. and beyond are shaping the future of cartridge production with innovative, reliable, and compliance-driven solutions. From boutique labs seeking cost-effective entry-level fillers to large-scale operators requiring precision and consistency, the right semi-automatic machine can dramatically improve efficiency and product quality.

To help producers navigate the options, we’ve compiled a list of the Top 10 Semi-Automatic Cartridge Filler Manufacturers in the USA (2025) — highlighting their business focus, product features, and unique strengths.

Top 10 Semi-Automatic Cartridge Filler Manufacturers in USA (2025) at a Glance

Longwill Machinery (Founded 2013)

Longwill Machinery is a professional manufacturer dedicated to providing complete cartridge filling and capping solutions for the vape, cannabis, CBD oil, and essential oils industries. Since its founding in 2013, the company has continuously expanded its product portfolio to serve businesses of all sizes—from boutique labs to high-output production facilities. While headquartered in China, Longwill has developed a strong presence in the U.S. market through global distribution networks, responsive after-sales service, and strategic partnerships with local distributors. Their focus is not only on delivering semi-automatic cartridge fillers but also on creating scalable solutions that can grow with a customer’s production needs.

Product Features:

High precision filling: Semi-automatic cartridge filling machines with accuracy up to ±0.01 ml, ensuring consistency in every cartridge.

Smart temperature control: Adjustable heating systems allow smooth handling of oils with different viscosities, from thin e-liquids to thick CBD extracts.

Broad compatibility: Designed to work with 510-thread cartridges, disposable vapes, pods, syringes, and even custom packaging formats.

Flexible operation: Machines can be operated manually, via foot pedal, or semi-automatically, making them suitable for both small-batch testing and continuous production.

Durable design: Built with food- and medical-grade stainless steel, ensuring easy cleaning and compliance with hygienic standards.

Strengths:

Longwill Machinery differentiates itself by combining precision engineering, affordability, and adaptability. Compared with many U.S. brands, Longwill offers a more cost-effective alternative without compromising quality. Its machines are particularly attractive for small and medium producers of cannabis and CBD cartridges who want reliable equipment that can deliver both accuracy and efficiency. The company’s global export experience means customers benefit from streamlined shipping, training support, and ongoing technical service. For businesses that need to balance production speed, accuracy, and budget, Longwill is positioned as a practical yet forward-looking partner.

Vape-Jet (Founded 2018)

Vape-Jet is a U.S.-based company that has quickly become a recognized name in the cannabis and vape hardware filling market. Established in 2018, the company set out to modernize cartridge production with a focus on automation, precision, and user-friendly operation. Vape-Jet not only manufactures semi-automatic cartridge fillers but also develops fully automated systems for large-scale producers. Its customer base ranges from small startups to multi-state operators who require equipment that can handle compliance demands while maintaining high throughput.

Product Features:

Jet Fueler semi-automatic cartridge filler with programmable settings for different volumes and oils.

Precision dosing combined with adjustable heat profiles for thick distillates and live resin oils.

Touchscreen interface with intuitive software for simplified operator training.

Designed to work with most 510-thread cartridges, pods, and disposables.

Strengths:

Vape-Jet stands out for its balance of innovation and reliability. Being U.S.-based, it provides fast technical support and training, which is a significant advantage for domestic producers. Its semi-automatic Jet Fueler is praised for accuracy, repeatability, and ease of use, making it a trusted solution for businesses that need to improve productivity without committing to fully automated systems.

Thompson Duke Industrial (Founded 2015)

Thompson Duke Industrial is one of the most recognized equipment suppliers in the U.S. cannabis industry. Founded in 2015, the company focuses exclusively on licensed cannabis producers and is widely respected for its compliance-driven approach. Thompson Duke’s equipment, including semi-automatic and fully automated cartridge fillers, is known for meeting rigorous GMP and cETLus certification standards.

Product Features:

SVH Semi-Automatic Filling Machine with adjustable fill ranges to handle multiple cartridge formats.

Integrated heating reservoirs that allow consistent filling of high-viscosity cannabis oils.

Ergonomic design for operator safety and reduced fatigue during long production runs.

Built with industrial-grade components for long service life.

Strengths:

The key strength of Thompson Duke lies in its regulatory compliance and reliability. Producers who need audit-ready cartridge filling machines often choose Thompson Duke because of its certifications and established credibility. Its semi-automatic fillers combine precision and flexibility, making them an excellent fit for mid-sized businesses operating under strict state regulations.

CNC Packaging Inc. (Founded 2017)

CNC Packaging Inc. is a relatively young U.S. manufacturer that specializes in compact and affordable filling equipment. Since 2017, the company has catered to small and mid-tier cannabis processors, offering semi-automatic cartridge fillers that are simple to operate and easy to maintain.

Product Features:

C-SOLO Semi-Auto Cartridge Filler, designed for filling 0.1–1.1 ml volumes.

Integrated heating options for thicker oils and concentrates.

Portable, bench-top design that is ideal for labs and boutique brands.

Quick setup and minimal operator training required.

Strengths:

CNC Packaging’s main advantage is its accessibility and low entry barrier. Startups and craft producers appreciate its straightforward machines that provide professional results without the heavy investment of fully automated systems. For businesses seeking scalability and simplicity, CNC Packaging offers a practical solution.

ProSys Fill LLC (Founded 1989)

With over three decades of experience, ProSys Fill LLC is an established U.S. company specializing in dispensing and filling systems across multiple industries, including pharmaceuticals, cosmetics, and adhesives. Its semi-automatic cartridge fillers are tailored to meet the demanding requirements of cannabis and CBD oil producers.

Product Features:

M10/30 Semi-Automatic Cartridge Filler with bottom-up filling to reduce air bubbles.

Snuff-back cut-off technology ensures clean and precise dosing.

Built to handle high-viscosity extracts and concentrates.

Industrial-grade construction designed for heavy-duty, continuous use.

Strengths:

ProSys is trusted for its engineering expertise and durability. Its machines are designed for businesses that prioritize consistency and reliability in large-scale production. With a history in regulated industries, ProSys is a safe choice for cannabis producers who want proven, long-lasting solutions.

CoolJarz (Founded 2011)

CoolJarz, based in California, has been serving the cannabis and vaping markets since 2011 with a strong focus on packaging and cartridge filling machines. Known for their high-output systems, CoolJarz machines are popular among mid- to large-scale producers aiming to maximize efficiency.

Product Features:

A10-HotShot™ 1500 Semi-Automatic Filler capable of filling up to 12,000 cartridges per day.

Heating systems designed to handle thick cannabis extracts.

Modular accessories such as trays and foot-pedal controls for flexible operation.

Compact but powerful design for continuous industrial use.

Strengths:

CoolJarz shines with its high throughput and scalability. Its semi-automatic cartridge filler is particularly suited for companies needing fast, large-batch production without fully transitioning to automation. Combined with solid U.S.-based support, CoolJarz is a reliable partner for growth.

USA Lab (Founded 2015)

Founded in 2015, USA Lab Equipment has built a reputation as a one-stop shop for cannabis and hemp processors in the U.S. market. While the company offers a wide range of lab tools — from extraction and distillation systems to chillers and glassware — its semi-automatic cartridge fillers have become particularly popular among small and mid-scale producers. USA Lab’s mission is to provide accessible, affordable, and practical equipment for startups, research labs, and boutique extractors who need reliable production tools without the premium price tag.

Product Features:

Semi-automatic cartridge fillers that handle volumes ranging from 0.25 ml to 2 ml, compatible with both 510-thread cartridges and disposables.

Portable, benchtop-friendly machines that fit into small-scale labs and pilot facilities.

Handheld filling guns for flexible applications and quick small-batch runs.

Designed for easy cleaning and low-maintenance operation, an advantage for lean teams.

Strengths:

The major strength of USA Lab is its combination of affordability and professional-grade performance. Its semi-automatic fillers are often chosen by early-stage cannabis entrepreneurs who want to enter the market without making six-figure investments. Beyond pricing, USA Lab supports operators with a broad product ecosystem, allowing businesses to source extraction, distillation, and filling solutions from a single supplier. This “all-in-one” advantage makes it especially valuable for vertically integrated operators.

Detroit Dispensing Solutions (DDS) (Founded 2018)

Detroit Dispensing Solutions (DDS) was founded in 2018 to specifically address the needs of the rapidly growing legal cannabis sector. Unlike many competitors that adapted machines from other industries, DDS built its cartridge and pre-roll filling systems from the ground up with cannabis oils and distillates in mind. The company emphasizes modularity and scalability, making it easier for businesses to grow production without scrapping their initial investment.

Product Features:

Semi-automatic cartridge fillers with customizable filling heads to adapt to various viscosities and container types.

Precision temperature control systems to maintain oil quality while ensuring smooth dispensing of distillates, live resin, or terpene-rich formulations.

Modular platforms that allow integration with conveyors, cappers, or future automation upgrades.

Robust stainless-steel and food-grade components to ensure compliance with cannabis industry regulations.

Strengths:

DDS is known for future-proofing its equipment. Many operators begin with DDS’s semi-automatic cartridge filler and later expand capacity by adding automation modules, ensuring that their investment grows alongside demand. This flexibility makes DDS a strong fit for scaling brands and multi-state operators who anticipate rapid production increases. Additionally, being based in Detroit — a hub for industrial engineering — gives DDS access to skilled manufacturing expertise, which translates into equipment that balances durability with modern cannabis-specific innovation.

Graco (Founded 1926)

Founded in 1926, Graco has nearly a century of experience as a global leader in fluid handling and dispensing technology. While the company serves diverse industries such as automotive, aerospace, food, and pharmaceuticals, it has also entered the cannabis sector by adapting its precision filling and metering systems for oils, concentrates, and cartridges. Graco brings industrial-grade engineering into an industry where equipment longevity and consistency are becoming more critical as businesses scale.

Product Features:

Semi-automatic filling equipment with high-precision pump technology, designed to deliver exact dosing across thousands of cycles.

Systems adaptable to cartridges, syringes, pods, and custom packaging formats.

Rugged construction designed for continuous operation in demanding production environments.

Advanced valve and pump technologies that minimize waste, dripping, or air bubble issues.

Strengths:

Graco’s biggest strength is credibility and cross-industry expertise. While many cannabis-focused equipment manufacturers are relatively young, Graco offers a proven track record of producing industrial dispensing systems that last decades. For cannabis companies transitioning from craft-scale to enterprise-level production, Graco represents a trusted partner that ensures compliance, repeatability, and scalability. Its reputation also gives investors and stakeholders confidence in long-term equipment performance.

Best Metering Systems (Founded 1990s)

Best Metering Systems (BMS) has specialized in metering and dispensing solutions for viscous and specialty fluids since the 1990s. While originally serving sectors like adhesives, sealants, and lubricants, the company has successfully applied its technology to the cannabis and CBD cartridge filling market. BMS differentiates itself by offering tailor-made semi-automatic cartridge fillers that are engineered around the specific needs of each client, whether they work with thin CBD oils or high-viscosity THC distillates.

Product Features:

Semi-automatic cartridge fillers equipped with precision metering pumps for consistent volume control.

Customizable filling parameters to accommodate different oil viscosities, terpene blends, and cartridge types.

Modular configurations that can expand into multi-head or automated systems.

Built with durability and accuracy in mind, reducing downtime and material waste.

Strengths:

The key strength of BMS is customization and technical flexibility. Unlike mass-market suppliers, BMS works closely with clients to design solutions that match their production requirements. This makes it an attractive option for brands with unique formulations or specialized cartridge designs. By combining decades of fluid-handling expertise with cannabis-specific adaptations, BMS provides precision-driven equipment that bridges the gap between craft operations and industrial production.

Conclusion

As the cartridge market becomes increasingly competitive, choosing the right filling partner is no longer just about price — it’s about precision, compliance, scalability, and after-sales support. Each of the companies on this list offers unique strengths, from U.S.-based compliance expertise to global engineering solutions, ensuring that producers of all sizes can find a machine that fits their needs.